Xinhua News Agency, Zhengzhou, May 4 th: Youth is brilliant in the Millennium.

    Xinhua News Agency reporter Shi Linjing

   On May 3, the Qingming Shangheyuan Scenic Area performed a performance of playing iron flowers. Xinhua News Agency (photo by Yuan Hang)

    The molten iron at 1600℃ turns into starlight all over the sky, and like the spring breeze blows away thousands of silver flowers … During the May Day period, in Shangheyuan Scenic Area, Qingming, Kaifeng, Henan Province, Pang Fei, a blacksmith after "90", scooped up the molten iron from the furnace and lifted it. Zhang Bao, a partner on the side, raised his paddle high and struck hard, which was thrilling and wonderful in an instant, attracting tourists to cheer.

    As one of the representative projects of national intangible cultural heritage, "Tie Tie Hua" is a folk cultural performance skill discovered by ancient craftsmen in the process of casting utensils, which is mostly spread in the middle and lower reaches of the Yellow River, especially in Henan and Shanxi, and has a history of more than a thousand years.

    This Chinese romance, which has been passed down for thousands of years, is also called "the game of the brave". Liu Xiaosong, a 45-year-old representative inheritor of the "Bianliang Tiehua Liu" in Kaifeng, Henan Province, was deeply involved. "In my impression, every year during the Chinese New Year or Lantern Festival, almost every household will burn some molten iron as fireworks." Liu Xiaosong said. Watching the elders play while the iron is hot makes young Liu Xiaosong obsessed with it. "With the development of society, fireworks have also become popular, and the technical requirements for playing iron flowers are very high. This skill has been interrupted in the village for more than ten years."

    In 2008, Tie Tie Hua was included in the list of representative projects of national intangible cultural heritage. Liu Xiaosong began to pursue the unique skill of striking while the iron is hot, and learned from teachers, visited and discussed with peers … In the process, more and more young people joined in. Pang Fei and Zhang Bao are a group of "post-90 s" who joined earlier. The reason why they decided to learn to play iron flower is very similar: it is bitter, but it is cool. "From an early age, I watched the older generation play iron flowers. Every time I heard the exclamation of the onlookers after the first iron flower was scattered in the air, I wanted to pass it on." Pang Fei said.

   On May 3rd, "post-90s" Pang Fei and Zhang Bao performed iron flowers in Shangheyuan Scenic Spot in Qingming Festival. Xinhua News Agency (photo by Yuan Hang)

    Although there is love, the high temperature of 1600℃ is always the most sad level for the blacksmith.

    Playing iron flowers usually begins with drawing water. Water is very similar to molten iron. Apprentices are qualified from the first one meter, three meters, to five meters until they hit the water to more than ten meters.

    We should not only train hard, but also practice accuracy. "Put the iron in the pottery furnace and keep burning carbon until the iron melts into water. The temperature of the molten iron just scooped out is very high, so performers need to be extra cautious when grasping the strike. If the strike position is inaccurate or the strength is not enough, the iron flower can’t reach a certain angle and height, and it is easy to burn. " Pang Fei said that it is common to practice being burned at first, and you will learn it when you are full of scalds.

    As an art form with unique Chinese charm, there is an increasing demand for the performance of Tie Hua. "Now all kinds of cultural exhibitions, art festivals, folk activities, etc. can see the shadow of the iron flower. We perform more than 1,000 performances every year on average." Liu Xiaosong said that in the Qingming Shangheyuan scenic spot in Kaifeng, there are nearly 10,000 people watching a show.

   On May 3, the Qingming Shangheyuan Scenic Area performed a performance of playing iron flowers. Xinhua News Agency (photo by Yuan Hang)

    While inheriting the ancient skills, Liu Xiaosong also innovated the performance content and form of Tiehua, incorporating folk elements such as dragon dancing and scientific and technological elements such as sound and photoelectricity. "In terms of raw materials, we have developed a new type of raw materials with large flowers, high brightness and flame retardant properties, which will die when it hits the ground, with strong environmental protection and high safety." Liu Xiaosong said.

    Today, Liu Xiaosong’s team is growing, and many post-90s and post-00s have joined the ranks. "If there is anything I want to learn, I will not refuse. Looking at these children, I feel that the iron flower can be passed down from generation to generation." Liu Xiaosong said.

    On the morning of May 4th Youth Day, Liu Xiaosong and his disciples came to Shangheyuan Scenic Area in Qingming Festival to prepare for the evening performance. Working in pairs, breaking carbon, catching fire and melting iron … "After 00", Zhai Xinzhuo looked at the skilled operation of his brothers and envied them. This is his second week of learning to play iron flower. At present, the height of drawing water has reached 10 meters.

    Zhai Xinzhuo’s eyes shone brightly when his brothers skillfully scooped up the hot molten iron and kicked it into the air with a paddle.

The phenomenon of sudden death has existed in human society since ancient times, and it is not a new concept in recent years. However, with the increase of social pressure and the acceleration of work rhythm, the incidence of sudden death is increasing year by year.

At the same time, the popularity of the Internet also makes us hear the news about sudden death more frequently.

What is sudden death?

The word "sudden death", as its name implies, refers to sudden and unexpected death.

Regarding the specific definition of "sudden", there are differences among professional institutions, and it is generally believed that this time period is between 1 hour and 48 hours. Take the World Health Organization (WHO) as an example, its definition of sudden death is: from symptoms to death, this process is completed within 24 hours.

Sudden death is an irreversible result, which means the end of life and cannot be redeemed. To effectively deal with sudden death, we need to understand the reasons behind it.

Life goes on because the heart keeps beating. Therefore, when the heart can’t beat effectively and can’t provide enough blood for important organs of the body, if the heart can’t beat effectively in time, sudden death may come.

According to the statistics of developed countries, about 90% cases of sudden death are cardiogenic. Of course, in addition, a small number of sudden deaths are caused by brain-derived, lung-derived, abdominal-derived, endocrine-derived and other factors.

What is the pathogenesis of sudden cardiac death?

To further subdivide sudden cardiac death, we can divide it into two categories: "coronary" and "non-coronary".

In the case of sudden cardiac death, coronary sudden death accounts for 56.78%~80%, and this phenomenon is more obvious in middle-aged and elderly people, and the main culprit behind it is coronary heart disease.

For those patients with a history of coronary heart disease, the risk of sudden death is four times that of ordinary people. In-depth exploration, we will find that 3/4 of sudden cardiac death is inextricably linked with coronary heart disease.

The formation of coronary heart disease is closely related to a series of bad health conditions and living habits such as obesity, smoking and three highs.

In particular, some patients’ symptoms of coronary heart disease are not obvious and are often mistaken for slight physical discomfort, but this invisible threat will greatly increase the risk of sudden death.

Although people over the age of 40 are the high-risk group of coronary heart disease, in recent years, the younger trend of this disease has become more and more obvious, and even young patients aged 25 have been reported to have coronary heart disease.

Taking snacks as dinner, drinks instead of water, lack of exercise, staying up late, endless consumption of the body, but never having a physical examination … Such a lifestyle may be quietly causing your coronary artery to fall into a crisis of blockage.

Before sudden death, the body will send out three important distress signals!

Before the critical moment of cardiac arrest comes, are there really symptoms that can be alarmed?

In fact, about 50% patients did not show any obvious symptoms before cardiac arrest. For the other half of cardiac arrest patients, they may experience some specific physical reactions or symptoms during the period from a few days to several hours before the sudden death. Although these signs are not absolute, they deserve our attention and vigilance.

Signal 1: Persistent chest pain or discomfort.

Chest pain is one of the most common symptoms of heart disease and an important warning signal before sudden death. This kind of chest pain may manifest as a feeling of oppression, tightness or dullness, and sometimes it may radiate to the left arm, neck, chin or back.

Persistent chest pain indicates that there may be coronary artery obstruction, leading to myocardial ischemia. At this time, all activities should be stopped immediately, and emergency calls should be made to strive for golden treatment time. Remember, time is life, and every minute of delay may increase irreversible damage.

Signal 2: Extreme fatigue and dyspnea

Extreme fatigue and unexplained dyspnea are also common signs before sudden death. If you feel extremely tired recently, even if you have enough rest, you can’t relieve it. At the same time, accompanied by slight physical activity, you will have difficulty breathing, which may be caused by the decline of heart function and the inability of your body to obtain oxygen effectively.

Extreme fatigue and breathing difficulties are the body telling you that the heart may be under heavy burden and unable to pump blood effectively. In this case, medical help should be sought immediately and relevant examinations should be carried out in order to detect and intervene potential heart problems at an early stage.

Signal 3: Arrhythmia and syncope

Arrhythmia, that is, the heartbeat is too fast, too slow or irregular, is also an important signal before sudden death. If you often feel flustered, palpitations, or sudden syncope, this may be an abnormal performance of cardiac electrical activity, which needs great attention.

Arrhythmia may cause the heart to fail to pump blood effectively, and in severe cases, it may cause syncope or even sudden death. If you or someone around you has symptoms of arrhythmia, you should immediately stop any activity and take a sitting or lying position to avoid falling. At the same time, you should see a doctor as soon as possible and have an ECG check for accurate diagnosis and treatment.

Although sudden death is threatening, not all of them are untraceable. Understanding and recognizing the distress signal of the body is the key to prevent sudden death. It is strongly recommended that once any one or more of the above symptoms appear, do not hesitate to seek medical treatment immediately.

Original title: "Emergency doctors remind: Before sudden death, the body will send out three important distress signals! 》

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Original Tian yi chi huo institute

It’s Zigong

Yanbang cuisine, by its name, feels like a heavy-flavored cuisine. The fact is true, salt-helped dishes are born of salt, and the characteristics of the cuisine are fragrant, spicy, fresh and heavy.

Yanbang cuisine, also called "Xiaohe cuisine" in the pedigree classification of Sichuan cuisine, takes Zigong in southern Sichuan as the center and also includes Yibin cuisine, Luzhou cuisine and Neijiang cuisine around it.

Zigong fried eel

01

Zigong in Sichuan

/Food nourished by salt resources/

Zigong is a prefecture-level city in Sichuan, and one of its subordinate districts is called ziliujing district. According to the older generation of salt workers, "gravity flow" is not an adjective, but a reality. Brine water is on the surface of the ground, gently cut a hole, and brine "gurgles" like a mountain spring.

Zigong people laughed at themselves: "This palm-sized place", at most, there were more than 10,000 salt wells, which showed that the well salt resources here were rich and the salt merchants’ trade was prosperous.

The salt needs to be boiled after it is beaten.

Under the prosperous trade, the taste of relying on salt to survive has grown: salt workers have to work hard, heavy oil and salt can ensure physical strength and fast meals, and they eat "salt workers’ dishes" with heavy taste.

Salt merchants are rich, paying attention to face and ostentation. They make the dishes carefully crafted by the chefs in your house known as "salt merchants’ dishes". Salt merchants’ dishes abandon some heavy tastes and have a light taste.

The heavy profit of salt drove businessmen from all over the world to gather in Zigong, where they set up provincial guilds, thus giving birth to "guild dishes" that gathered local characteristics and absorbed the practices of various factions.

Hot pork intestines with heavy mouth

Light and tasty chicken tofu pudding

Maybe many people haven’t seen the salt well with their own eyes. It doesn’t have a wide wellhead and water surface visible to the naked eye as most people think. Most of the bittern is buried several hundred meters or even thousands of meters from the ground. People use all kinds of heavy tools to dig the well bit by bit, 5 years, 10 years, 20 years, 200 meters, 300 meters and 800 meters, until the bittern water is produced, and the wellhead is no bigger than a sea bowl.

To draw bittern is to put a long bamboo tube deep into the bottom of the well, pour bittern and lift it to the ground. Whether drilling wells or extracting brine, you need to rely on ladders, winches and cows up to tens of meters. The work on the well is around the clock, and so are the cows pulling the winch. It takes about 50 turns to draw a bucket of bittern. Because of the excessive labor intensity, many cows will die in less than one year.

Crane of Zigong Ancient Salt Well | Phreakster 1998/ wikipedia

Dead cows can’t be wasted. For salt workers who are also working hard, beef is an excellent energy source. Many traditional beef dishes in Yanbang cuisine were born.

Nowadays, boiled beef, which is common in major Sichuan cuisine restaurants, is one of the representatives of salt industry dishes. The spicy taste is thick, smooth and palatable, and the flavor is strong. The enthusiasm of boiled beef is very similar to that of Sichuan people.

Boiled beef | flickr Liu Milu

02

Authentic yanbangcai

/Not just spicy and spicy/

When I went to Zigong a while ago, I was lucky enough to invite a famous local chef to cook a table of authentic salt dishes for us. The impression that salt dishes are spicy and heavy was greatly subverted, and we can also get a glimpse of the reason why Sichuan cuisine can go out of Sichuan and conquer the world.

■ Boiled beef

Let’s start with boiled beef. Is this dish particularly common? But this time I ate something unusual.

At present, the common practice of boiling beef in water is to fry lettuce tips, bean sprouts and other vegetables first, then put the pickled beef in a pan and lubricate it, and finally put it in the sauce and fry it together, and finally pour oil on the table.

However, in the traditional way of boiling beef, you should first stir-fry the ingredients, then stir-fry the vegetables. The sauce has the smell of vegetables, then use it to cook the beef, and finally put in the knife-edge pepper and serve it with oil.

Traditional boiled beef

Although it is only a small difference in steps, it actually tests the chef’s temperature. Stir-fry vegetables first, then beef. If you don’t master the heat well, it will burn. Therefore, for the convenience of the map and the stability of the product, vegetables and beef are usually cooked separately in general restaurants by default.

In the traditional way, vegetables, beef and sauces are combined, and you have me and I have you, and the hemp, spicy, fresh, fragrant and fragrant are compound and rich in layers-this should be the reason why boiled beef is the first Sichuan dish to catch fire.

■ Fireside beef

Another beef dish, which can be served as a cold dish or as a snack, is fireside beef.

Legend has it that this is also the invention of salt workers. In the old days, salt merchants paid beef as part of their wages to salt workers. The salt workers first soaked large pieces of beef in brine to taste, then cut them into extremely thin, almost light-transmissive slices, salted them, spread them flat on a shelf and dried them, and then smoked them by the fire with cow dung as fuel, from which came the "fireside beef". The dried beef slices are crisp but not cotton, and the entrance is crisp and tough.

Huobianzi beef

According to the chef, the process of this dish is not complicated, but it needs a lot of care and experience, because if the beef is cut thin and then spread flat on the bamboo sticks for air drying and smoking, if the experience or patience are insufficient, the meat slices will not be formed, and it will be impossible to become a dish. Therefore, this is all meticulous work, which is very wasteful.

Sichuan has always been one of the places where beef is eaten the most and can be eaten in a variety of ways. Hot yellow throat, hot hairy belly and other dishes made by cattle in the water are also the favorite of salt workers. While salt workers were boiling, frying and baking, chefs working for wealthy businessmen and nobles began to disassemble and cook cows in more detail.

■ Yipin Niutoufang

Yipin Niutoufang is considered as a typical official dish of Shanghe Gang in Sichuan cuisine, and it can also be found in the guild dishes of Yanbang.

Niutoufang is made by burning the skin at the top of the cow’s head to remove the rough epidermis and hairy roots. After a long time, the meat is thick and soft, the gum is elastic and tough, and the aroma is solid and rich. Niutoufang is by no means a stunning taste, but a thick and delicious food in a silent place. Now there are only a handful of chefs who can produce this dish.

Yipin niutoufang

This delicate idea has also been used in other dishes-liver cake soup, a famous and almost lost old dish.

■ Liver cake soup

Liver cake soup is one of the three clear soup dishes in Sichuan cuisine. It is made of liver, clear as water and mellow in taste. Luo Chengji, a scholar of Zigong literature and history, once mentioned "mushroom liver ointment soup" in his works. If it is not difficult for many professional chefs to cook clear soup like water, then making "liver cream" is not the secret that everyone can master.

Liver cake soup

This time, in the hands of Zigong famous chefs, we are also fortunate to taste it. For this dish, the chef began to cook soup from 9: 00 in the morning, with old chicken, ribs, chicken feet, lean meat and ham as the base materials, and kept it boiling for 7 hours with minimal fire.

And the other protagonist: liver, the traditional practice is to use pig liver, and modern chefs will choose a more delicate foie gras. The method of making liver cake was gently taken by the chef, and it was "steamed". In fact, there are secrets in seasoning and modulation. Of course, the cooking skill is still the key. If you don’t master the cooking well, the liver cake is too tender or too rough, and you can’t form a delicate and dense taste.

When the broth has been boiled for enough time, add chicken breast meat and pork meat to absorb blood foam impurities, and then filter for several times until the soup is clear as water and yellowish in color. Then put the shaped and flavored liver cake into the clear soup and steam it in the cage for several minutes before the liver cake soup is ready.

In this dish, the taste of soup is very light, and all the delicious ingredients have been melted into the soup. The elephant is invisible, as elusive as a shadow, and people can’t help but want to catch up and take another look. The entrance of liver cake is delicate and mellow, which is in contrast with the lightness of soup.

However, in the eyes of local people, the dish that can best get through the upper and lower classes in Zigong is the rabbit.

Tutu is so cute, it must be delicious.

There are too many ways for rabbits to eat in salt dishes, such as cold rabbit, double pepper rabbit, dried pepper rabbit, dry pot rabbit, soaked rabbit, scalded rabbit …

Dried pepper rabbit

There were two rabbits in the chef’s banquet: fresh pot rabbit and scalded skin rabbit.

■ Fresh pot rabbit

Fresh pot rabbit, strictly speaking, belongs to the new school of salt-help dishes, which evolved from the traditional double pepper rabbit. No Zigong chef is not perfect in cooking rabbits.

Double pepper rabbit

Fresh pot rabbit is seasoned with fresh pepper, and the soup is used as the base. It is hot and spicy, heavy oil and heavy salt, and it must be served with two bowls of white rice, which is really enjoyable. Diners joked: it’s really a salt-helped dish, so I’m too willing to put salt in it, so I have to use a big bowl of rice to match it. This combination means that I have to do something.

Xianguotu

■ Scalded rabbit

The scalded rabbit is a typical traditional salt merchant dish. "Hot" is actually boiled. The beauty of the word "hot" is that the rabbit meat is delicate. After a short period of boiling, the rabbit meat with a little oil is smoother. It is slightly salty and tender when eaten directly, and the taste is progressive step by step when dipped in water, which is enough to satisfy the guests from all walks of life.

Scalded rabbit

In addition, because of the Tuojiang River, Minjiang River and Fuxi River, in the eyes of the salt chef, fresh river and waterfowl can also have ever-changing tricks.

Salt helps a duck. Take an old duck, remove its bones, stuff it into pork belly, ham and dried bamboo shoots, steam it, and scoop it with a spoon when eating it. It is unusually soft and delicious. Eat loach cold, fry fresh loach first and then fry, let it cool before eating, crispy with glutinous rice, heat and seasoning are indispensable; The young ginger frog, which Zigong people think is small and flexible, is fresher than the bullfrog with thick meat. After the young ginger is fried with the frog, its position is not only an auxiliary material, but often robbed by everyone with the frog …

Young ginger frog

Only after eating this meal did I know that the folk saying that "a salt merchant has a dish and a salt worker has food for half a year" is not empty talk, but it does not mean how valuable ingredients salt merchants like.

Just like the "eggplant" that surprised granny Liu, eggplant and old hen are nothing but ordinary things, even if abalone has wings and belly, it is not rare. What is really rare is to find someone who is willing to spend time and effort to cook ordinary food to amazement. That is the gorgeous chapter seen in the ordinary.

Burning white

* Thanks to Zigong Museum (Ji Chengjing), Zigong Food and Beverage Association, China cooking master Wang Guangkai, China cooking master Zhang Liquan, and famous chef Tonge of Yanbang cuisine for their support to this article.

* This article does not indicate that the source images are from Duoduo and Lamian Noodles.

I can eat a bowl of white rice with this article!

Original title: "Sichuan pilgrimage site, two words-of course not Chengdu! 》

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　　Cctv newsOn August 16th, CCTV’s "International Sharp Review" broadcast an article entitled "Global investors and traders, welcome to take the" express train "developed by China", which was reprinted by many overseas media.

　　From 16 to 18 August, Russian Siberian News Network, European Times German Network, German-Chinese Report website, French LCF Radio facebook account, Spanish Radio International website, Italian Radio We website (facebook, twitter), Turkish Economic Observation Network, Albanian National Radio and Television website, Czech Today Information Network, Kazakhstan Industrial News website, Facebook account of Tanzania Africa Media Group, facebook account of Jordan Global Radio, Chinese PT Portal, Chinese Headline APP, Portuguese New Newspaper APP(facebook, twitter), Nordic Times website, Europe-China United Times website, European Union Chinese website, Africa Times website, West Africa online website, Japanese Chinese business website, Greek China website and many other overseas media have forwarded them one after another. From August 17th to 18th, this article was also published in Hong Kong Ta Kung Pao, Hong Kong wenhui network and Hong Kong Business Daily. The main reports are as follows:

　　China recently released economic data for July, showing that the total import and export volume reached 2,602.8 billion yuan, up 12.5% year-on-year, and the growth rate was 8.2 percentage points higher than that of last month. Among them, exports were 1,389.9 billion yuan, up 6.0%, 3.0 percentage points faster than last month; Imports reached 1,212.9 billion yuan, up 20.9%, 14.9 percentage points faster than last month. Import and export balance, the trade surplus of 177 billion yuan, 83.9 billion yuan narrower than last month.

　　China’s import and export growth accelerated in July, and its trade surplus narrowed, indicating that China’s measures to open wider to the outside world are releasing more dividends. As the Supreme Leader of president, China said at the 2017 annual meeting of the World Economic Forum, China’s development is an opportunity for the world, and Chinese will not commit "red eye disease". People from all countries are welcome to take the "express train" and "free ride" developed by China. Since the Chairman of the Supreme Leader announced a new round of opening-up measures at the 2018 annual meeting of Boao Forum for Asia in April this year, various measures have been intensively implemented and the commitments to opening up have been fulfilled one by one. In the second half of the year, China will also bring two major benefits to the world: First, the "Huluntong" will be opened during the year to further open the capital market; Second, the first China International Import Expo will be held in Shanghai to provide a larger market and trading platform for global trading partners and create new market demand.

　　Look at Huluntong first. It refers to the interconnection between Shanghai Stock Exchange and London Stock Exchange. Previously, China had launched Shenzhen-Hong Kong Stock Connect and Shanghai-Hong Kong Stock Connect in 2014 and 2016 respectively, which enhanced the margin financing and securities lending capacity of the securities market between Hong Kong and mainland enterprises. "Huluntong" is the first step to connect the world’s largest emerging market with the oldest international mature market, which will not only make China’s securities market more international and legal, but also provide greater opportunities for British enterprises to deeply participate in China’s capital market. International investors can get more convenient financial support through "Huluntong" and increase opportunities for third-party market cooperation. In a recent meeting with British Foreign Secretary Hunt, China Prime Minister Li Keqiang stressed that the two sides should take the opening of the "Shanghai-Luntong" project this year as an opportunity to actively cultivate new growth points for cooperation and achieve mutual benefit and win-win results.

　　Undoubtedly, "Huluntong" will become a new footnote for the opening of China’s capital market. Prior to this, the first futures product opened to the outside world from China — — Crude oil futures are listed on the Shanghai Futures Exchange, and the A shares are included in the morgan stanley capital international Emerging Markets Index; From allowing foreign investors to hold 51% shares in joint-venture securities companies and fund companies for the first time to further liberalizing the scope of foreign investors’ participation in A-share trading, a series of opening-up actions in China’s capital market have attracted increasing foreign capital inflows.

　　According to the data of the State Administration of Foreign Exchange of China, the cross-border capital inflow of foreign securities investment in China in the first half of the year has tripled year-on-year. According to the statistics of China Securities Regulatory Commission, from January to July 2018, the accumulated net inflow of overseas funds into the A-share market was 161.6 billion yuan. Despite the intensification of global trade friction in June and July, the net inflow of overseas funds into the A-share market still reached 49.8 billion yuan. Recently, morgan stanley capital international Company released the index evaluation report for August 2018, and decided to increase the inclusion factor of the existing A shares from 2.5% to 5%, which will account for 0.75% of the morgan stanley capital international emerging market index.

　　In capital market, confidence is more important than gold. The increasing inflow of foreign capital shows the confidence in China’s economic development. In fact, foreign investors have been waiting for China’s huge financial market and profit margin for a long time. Once the "Huluntong" is opened this year, they will undoubtedly share a bigger "cake".

　　At the same time, as China’s global trading partners, they will also get more dividends from the first China International Import Expo held in Shanghai in November. As the world’s first national-level exposition with the theme of import, its role in promoting today’s world trade cooperation is unquestionable. At present, more than 2,800 enterprises from more than 130 countries and regions have registered to participate in the exhibition, and it is estimated that there will be 150,000 buyers worldwide. It is reported that more than 30 overseas enterprises have signed up in advance to participate in the second China International Import Expo next year.

　　Keen exhibitors have seen that Chinese’s demand for a better quality of life and high-quality economic development is becoming a new kinetic energy for the growth of the global consumer market and a new space for enterprises from all over the world to create wealth. It is estimated that from 2017 to 2022, China will import 8 trillion US dollars of goods and absorb 600 billion US dollars of foreign investment, with a total foreign investment of 750 billion US dollars and 700 million outbound tourists. At a time when global trade and investment are blocked by protectionism and unilateralism, the above-mentioned good news from China is undoubtedly a great boost to the confidence of enterprises in various countries. According to the annual white paper "American Enterprises in China" released by American Chamber of Commerce in China at the end of May, nearly 60% of the interviewed enterprises listed China as one of the top three investment destinations in the world, one third of the members planned to expand their investment in China by more than 10%, and 46% of the respondents expressed confidence that the China government would further open its market to foreign investment in the next three years, which was higher than 34% in the same period last year.

　　Looking around the world, China not only has a huge market with a population of nearly 1.4 billion, but also has the determination and actions to support trade liberalization and investment facilitation. I am afraid it is difficult for investors and traders from all over the world to find a bigger market and more opportunities than China. Now, what they need to do is to seize the opportunity and board the "express train" of China as soon as possible.

　　A number of overseas media forwarded "International Sharp Review" articles:

Russian Siberian News Network forwarded on August 17, 2018

The German-Chinese Report website was forwarded on August 16, 2018.

Italian Radio We website (facebook, Twitter) forwarded on August 16, 2018.

The website of Albanian National Radio and Television Station was forwarded on August 16, 2018.

The facebook account of Tanzania African Media Group was forwarded on August 16, 2018.

Jordan Global Radio facebook account forwarded on August 16, 2018

Hong Kong Ta Kung Pao was published on August 17, 2018

Wenhui network, Hong Kong forwarded on August 17, 2018.

Forward by Hong Kong Business Daily on August 18, 2018

Since the reform and opening up, especially since the 18th National Congress of the Communist Party of China, with the sustained and stable economic development, China’s industrial chain supply chain has made great progress, its core competitiveness has been continuously enhanced, and its independent and controllable ability has been further enhanced. China’s position in the global industrial chain supply chain continues to climb, which provides strong support for accelerating the construction of a modern economic system and promoting high-quality development.

At the same time, however, the unbalanced development of China’s industrial chain supply chain is more prominent, and different industries have obvious differences in development speed, development stage and modernization level. In particular, the world has entered a new period of turbulence and change, the game between big countries has intensified, the suppression and containment from outside may escalate at any time, the risk of "chain sticking" and "chain breaking" has increased, and the trend of "decoupling" is looming, which brings great challenges to the reliability and security of China’s industrial chain supply chain. Therefore, we must adhere to the bottom line thinking, plan ahead, speed up the short board, strong and weak items, focus on improving the resilience and safety level of the industrial chain supply chain, and firmly grasp the development initiative in our own hands.

First, accelerate the realization of high-level scientific and technological self-reliance. Based on independent innovation, we should make good use of the remarkable institutional advantages of "a national chess game" to concentrate on doing great things, give play to the basic and strategic supporting role of education, science and technology and talents, take the national strategic demand as the guide, gather strength to carry out original and leading scientific and technological research, speed up the breakthrough and self-control of key core technologies, reduce the dependence on foreign technologies, break the situation that key core technologies are subject to people as soon as possible, and make the supply chain of industrial chain "complement, extend, consolidate and strengthen"

The second is to strengthen the construction of the industrial chain supply chain ecosystem. It is necessary to give play to the leading role of scientific and technological innovation, solve a number of "stuck-neck" problems as soon as possible, open up blocking points and solve difficulties, especially to fill in outstanding shortcomings such as basic software, core hardware and basic raw materials, accelerate the improvement of the modernization level of industrial chain supply chain, and realize independent control of industrial chain supply chain; Consolidate and enhance the international leading position of traditional advantageous industries, build a coordinated industrial chain supply chain system with high, medium and low end, and enhance the toughness of industrial chain supply chain; Actively promote the international cooperation of industrial chain supply chain, establish an industrial chain supply chain ecosystem with China’s industrial chain supply chain as the core and radiate many aspects, and continuously enhance the international influence of China’s industrial chain supply chain.

The third is to continuously stimulate the vitality of market players. To improve the resilience and safety level of the industrial chain supply chain, the market subject is the core. Promote a better combination of effective market and promising government, create a market-oriented, rule-based and international first-class business environment, boost the development confidence of market participants, enhance their expectations, give full play to the engine function and radiation-driven role of leading enterprises, promote the mutual support and coordinated development of industrial chain and supply chain, create a number of "specialized and innovative" enterprises, breed more new industries, new models and new formats, form more new growth poles and points, and create new advantages of industrial chain and supply chain.

(national academy of economic strategy researcher Zhang Deyong)

(Central Radio and Television General Station CCTV Network)

CCTV News:Recently, at the meeting of the Dispute Settlement Body of the World Trade Organization held in Geneva, Switzerland, the United States was convicted of violating WTO rules, but instead, the United States used the arbitration institution to "shut down" to appeal and tried to shelve the execution of the ruling indefinitely, which was severely denounced by many WTO members.

At the closed meeting held on January 27th, five members, namely China, Norway, Switzerland, Turkey and Hong Kong, China, set eight topics, demanding that the plenary session adopt five rulings of the expert group on the violation of the new regulations on the origin marking of Hong Kong goods imposed by the United States on imported steel and aluminum products under Article 232, and demanding that the United States cancel the illegal measures. The United States appealed all five rulings before the meeting.

But in fact, since 2019, the United States has repeatedly unilaterally obstructed the selection of judges of the WTO Appellate Body, and the WTO Appellate Body has fallen into a state of complete paralysis after the expiration of the previous judge in November 2020.

According to the minutes of the meeting published by the WTO, the permanent representative of the European Union to the WTO said at the meeting that the WTO arbitration institution was "paralyzed" because of deliberate sabotage by the United States, and it was impossible to hear these appeals at present, and the United States was actually abusing its right of appeal. Abuse of the right of appeal does not help to resolve trade disputes.

The Permanent Representative of Canada to the WTO said at the meeting that all parties to trade disputes must make every effort to find acceptable solutions and fulfill their good faith commitments under the Understanding on Dispute Settlement Rules and Procedures. The suspension of the Appellate Body has brought unfairness and short-term advantages to some members.

　　　　　　 The Permanent Representative of China to the WTO said that it seems that the United States will refuse to implement any unfavorable ruling involving "national security exception", which violates the principle of "pacta sunt servanda". These disturbing behaviors in the United States clearly depict the image of the implementer of unilateral bullying, the destroyer of multilateral trading system and the disruptor of global industrial chain supply chain.

　　　　　　 What is the ruling of the United States to appeal this time? In December 2022, the WTO released the report of the expert group on the dispute settlement mechanism, ruling that the measures taken by the United States to impose tariffs on imported steel and aluminum products in 2018 violated WTO rules and suggested that the United States should correct them. In March 2018, then US President Trump imposed tariffs of 25% and 10% on imported steel and aluminum products on the grounds of safeguarding national security according to Article 232 of the US Trade Expansion Act of 1962. This decision not only led the countries concerned to file a complaint with the WTO, but also the major trading partners of the United States introduced retaliatory measures. In November 2018, the WTO Dispute Settlement Body agreed to set up an expert group to review the steel and aluminum tariff measures announced by the United States to confirm whether the measures violated WTO rules. It was not until last December that the expert group of WTO dispute settlement mechanism issued its ruling.

　　　　　　 The unilateral trade bullying behavior of the United States has aroused more and more opposition around the world. Some media commented that the United States has now become the biggest destroyer of the international trading system.

　　　　　　 Headquarters reporter Yi Xin:For a long time, the United States has been waving a trade stick at other WTO members on the grounds of "national security" and frequently violated WTO rules. The research report on WTO dispute adjudication shows that by far, the United States is the most "unruly", and two-thirds of WTO violations are caused by the United States. When the WTO expert group ruled that the United States violated the rules, the United States took advantage of the current deadlock in the appointment of members of the WTO Appellate Body to appeal the ruling, so as to evade its obligations. The WTO Appellate Body’s "shutdown" and the paralysis of multilateral trade arbitration institutions are precisely caused by the United States’ insistence on obstructing the selection of judges despite the opposition of more than 100 WTO members. At the US trade policy review meeting held by the WTO in December last year, many WTO members expressed serious concern and dissatisfaction with the US trade policy.

Convicted of violating WTO rules, instead of executing the ruling, the United States appealed by using the "shutdown" of the appellate body, trying to put the execution of the ruling on hold indefinitely.

As an arbitration institution for trade dispute settlement, the Appellate Body is known as the "jewel in the crown of WTO" and it is an important part of the WTO dispute settlement mechanism. It has seven permanent seats for judges, each of whom has a term of four years and can be re-elected once. According to the WTO, cases of trade disputes must be tried and decided jointly by three judges. If the number of judges is insufficient, they can’t accept any new cases, and they will fall into a state of "stopping".

One of the most prominent features of the Appellate Body of WTO is its independence. Under this mechanism, all 164 WTO members, regardless of their size, can obtain equal rights to appeal or defend themselves. However, it seems that the United States has always regarded itself as an exception and repeatedly abused the "one-vote veto" to arbitrarily obstruct the start of the selection process for new judges of the Appellate Body.

Since 2017, the United States has frequently blocked the start of the selection process for new judges of the WTO Appellate Body.

In 2017, three of the seven judges of the Appellate Body ended their terms, but the United States has always blocked the appointment of new judges. Counting this time, in the past two years, the United States has said no to the selection of new judges for 30 consecutive times.

In 2018, the United States vetoed the appointment of Mauritian judges for a second term by one vote, leaving only three judges in the WTO Appellate Body. Three people are also the bottom line for the appellate body to operate. In order to avoid the "lockout", in that year, 67 WTO members demanded that "the selection process for new judges of the Appellate Body should be started as soon as possible". However, the United States rejected this proposal.

In November 2019, at the regular meeting of the WTO Dispute Settlement Body, 117 WTO members once again suggested that the process of selecting new judges of the Appellate Body should be started immediately, which showed the strong political will of most members to restore the Appellate Body. However, the United States is still bent on its own way.

On December 9, 2019, the United States once again unilaterally obstructed, resulting in a draft resolution on the reform of the Appellate Body not being passed, and the selection of new judges was once again blocked.

Due to the inability to select new judges in time, from December 11, 2019, only one judge of the Appellate Body was in office, and the Appellate Body was in a state of "stopping".

　　　　　　 On November 30, 2020, the last member of the Appellate Body officially expired. At this point, all members of the Appellate Body have left their posts.

What is the core reason for the United States to do so in the face of non-implementation of WTO rulings, non-compliance with rules and deliberate sabotage? What kind of bad influence will it have? Let’s listen to the interpretation of special commentator Su Xiaohui.

Su Xiaohui, a special commentator, said that many countries see that the United States has a kind of "double standard" behavior towards rules, and they will use it if they agree, and abandon it if they disagree. At the same time, they will try their best to safeguard American hegemony by taking the leading role in rule-making and use American bullying in trade. This kind of behavior interferes with the development of the world economy and harms others, which is also the fundamental factor behind everyone’s rebound against the United States.

On January 10 th, a book called"Stop issuing performance pay scheme for COVID-19 project"The document was circulated on the Internet and signed by Beijing Kexing Zhongwei Biotechnology Co., Ltd., which mentioned that the company’s COVID-19 vaccine has been completely discontinued and the company has no COVID-19 vaccine products for sale at present.

At noon on January 10th, Jimu journalist called the product consultation hotline of Kexing Holding Biotechnology Co., Ltd., and the staff confirmed it.Kexing’s COVID-19 vaccine has been discontinued. If you still need to inject this product, you should ask the local CDC if it is in stock.

It is worth noting that there are still a variety of vaccines for new strains that can be injected in various parts of China.

Kexing COVID-19 vaccine has been discontinued.

Many companies have "got off the bus" before.

According to Jimu News, on January 10th, a document named "Stop Issuing Performance Pay Scheme for COVID-19 Project" was spread on the Internet. The date of signing the scheme was January 9th, and it was stamped with the official seal of Beijing Kexing Zhongwei Biotechnology Co., Ltd., which mentioned that at this stage, the company has stopped production of COVID-19 vaccine and the company has no sales of COVID-19 vaccine products at present, and the company decided to stop issuing performance pay for COVID-19 project for existing employees from January 2024.

Beijing Kexing Zhongwei Biotechnology Co., Ltd. is a subsidiary of Kexing Holding Biotechnology Co., Ltd. At noon on January 10,The staff of the product consultation hotline of Kexing Holding Biotechnology Co., Ltd. confirmed that at present, the COVID-19 vaccine of Kexing of the company has been discontinued. If the product needs to be injected, it is necessary to ask the local CDC if it is in stock.As for the authenticity of the online transmission of "Stop Sending Performance Pay Scheme for COVID-19 Project", the other party said it was unclear, and she was only responsible for product consultation.

In fact, since 2023, a number of companies that have been developing COVID-19 vaccine have either announced a change of direction or stopped investing, or their financial data reflect the "sequela" of "slow sales" of COVID-19 vaccine.

On July 19th, 2023, COVID-19 Microorganism Tianci Factory, one of the three musketeers of domestic mRNA vaccine, suspended its trial operation because there was no demand for vaccine production in the near future. All this was only two and a half years after it obtained the clinical approval of COVID-19 mRNA vaccine in January 2021. At that time, COVID-19 mRNA vaccine of Microorganism was the second domestic COVID-19 mRNA vaccine that entered the clinical stage.

For COVID-19 vaccine, Clover Bio, a Hong Kong-listed company, can be described as "putting all your eggs in one basket". In June, 2022, Clover Bio announced that it would give priority to the allocation of all resources to COVID-19 vaccine project, suspend the investment in the other three clinical pipelines, and reduce the investment in non-COVID-19 projects and new projects. In December 2022, COVID-19 vaccine SCB-2019(CpG 1018/ aluminum adjuvant), a recombinant protein of clover, was put into emergency use in China, and was officially launched for the first time in February 2023.

However, in the semi-annual report of 2023, Clover Bio said that due to the ever-changing and low overall demand for COVID-19 vaccine from China and countries around the world since 2023, the company predicted that COVID-19 vaccine sales in 2023 would not bring meaningful financial contribution. Its vaccine layout turned to respiratory diseases such as RSV and influenza.

In April 2023, the "low-cost operation notice" of Shangyao Kangxinuo was spread on the Internet. The content of the notice shows that it is decided to suspend the production line from April 4 for a period of 180 days. According to Red Star News at that time, the staff of Kangxinuo patient answering hotline introduced that the COVID-19 (vaccine) production line here was temporarily suspended, and there was no problem here at the headquarters. Now the demand for COVID-19 vaccine is not so great, so the production line of Shanghai Kangxinuo COVID-19 (vaccine) has been temporarily stopped, which will not affect other aspects.

Chang Rongshan: Inactivated vaccine is not recommended at present.

In February 2023, a research paper published by domestic researchers in the latest issue of China CDC Weekly stated that,"Although the protective efficacy of the third dose of Kexing inactivated vaccine can be improved to more than 70% within one month after homologous inoculation, its predictive efficacy will gradually decline to less than 50% after six months."

For COVID-19 infected people whose clinical endpoint is "COVID-19’s symptoms", the research results show that after 28 days and 6 months of intensive immunization, the protective effect of three doses of inactivated Kexing vaccine is only about 30% and 10%. Among them,The predicted protective effect of three doses of Kexing inactivated vaccine on Omicron BA.4/5 is even lower.

According to the interface news, virologist Chang Rongshan reminded that,Inactivated vaccine is not recommended at present.It pointed out that the antigenicity of the current epidemic strains has changed greatly, and the effect of inactivated vaccine will be much worse than that of other technological vaccines."It is best to play mRNA vaccine and recombinant protein vaccine."

According to JingJing. com, Xu Yue, an insider of a company that had previously researched and developed vaccines in COVID-19, said, "The research and development cost is one aspect, but the key is that you have developed it, and the virus has mutated, so the research and development speed can’t keep up at all. Vaccine iteration is too fast, and enterprises really can’t afford it, especially the cost of clinical trials. Before it is commercialized, the vaccine will be outdated first. "

Xu Yue told reporters that unlike the flu virus, which may go round and round, Covid-19 has been upgrading all the way, and the popular virus will not come again, and the old virus will not come. Therefore,Once the new COVID-19 vaccine appears, the old vaccine can be said to be "out of the historical stage".

A number of XBB vaccines were approved for use.

However, people’s willingness to vaccinate has obviously decreased.

According to Jingjing.com, on December 28th, 2023, the National Health and Wellness Commission held a press conference on the prevention and treatment of respiratory diseases in winter. Peng Zhibin, director of the Department of Respiratory Infectious Diseases of the Infectious Diseases Management Office of China CDC, said that recently, the spread of JN.1 (the second-generation sub-branch of BA.2.86 mutant in Omicron, Covid-19) has risen rapidly abroad and has become the main epidemic strain.

"The mutant JN.1 belongs to Omicron. Recently, according to the existing evidence, the World Health Organization believes that JN.1 has strong transmission ability and immune escape ability, but there is no evidence to suggest that its pathogenicity is enhanced. Previous infection and vaccination with XBB (Omicron subtype variant strain) vaccine have a cross-effect of immune protection, and it is predicted that the public health risk brought by it is low. " Peng Zhibin said.

At present, many XBB vaccines have been approved for emergency use in China. In June, 2023, the recombinant trivalent Covid-19 (XBB+BA.5+Delta mutant) trimer protein vaccine (hereinafter referred to as WEEK XBB vaccine) was put into emergency use in a certain range. In December, companies such as Shenzhou Cell, Kangxinuo and Livzon Group also announced that COVID-19 vaccine was included in emergency use.

According to the interface news, a domestic vaccine industry practitioner said,At present, the proportion of people’s willingness to vaccinate COVID-19 vaccine has obviously decreased, and the official has not clarified the requirements for vaccination indicators.All this makes "promoting vaccination in COVID-19" less urgent than before, which reduces the motivation of CDC. He said, "For example, if a company has a product approved, as long as it is developed and produced, the company will definitely want to be recognized in the market, and there is no situation in which the company is not enthusiastic. But in fact, from the step of bidding access, many provinces and cities have no enthusiasm. "

Rong Shan, a virologist, also said that the public is not willing to vaccinate COVID-19 vaccine at present. If COVID-19 vaccine is purchased, but not many people come to vaccinate it, it will easily lead to a backlog. Unlike ordinary commodities, vaccines have strict requirements for transportation and storage, and they will be wasted if they are not used after expiration.

Original title: Kexing COVID-19 vaccine has been discontinued! Many companies have long since "got off the bus", inactivated vaccines have not been recommended, and many XBB vaccines have been approved.

　　The reporter learned from the media briefing of the 2021 China International Fair for Trade in Services Telecom, Computer and Information Service Exhibition held on August 30th that the 2021 China International Fair for Trade in Services Telecom, Computer and Information Service Exhibition will be officially launched in Hall 9 of Beijing Shougang Park from September 3rd to 7th, showing the scientific and technological innovation and development achievements of the electronic information industry to the audience.

　　As one of the eight industry special exhibitions of this year’s Service Trade Fair, the special exhibition area of telecommunications, computer and information services is located in Hall 9 of Shougang Park, with a total exhibition area of 9,600 square meters. There are four characteristic sections: 5G communication service, information service, ultra-high definition audio-visual service and "carbon neutral" green technology service. There are 79 exhibitors, including 67 domestic exhibitors and 12 international exhibitors.

　　Four major operators jointly build a 5G telecom zone

　　The 5G communication service section will show the applications and cases of 5G in various fields. The plate focuses on "5G+ industry" and adopts the way of "exhibition+experience" to show the new applications, new markets and new prospects brought by 5G. The 5G communication service exhibition area creates an immersive sensory experience through a modern exhibition hall with a sense of science and technology. The exhibition area focuses on the high-tech elements of "Everything Smart" of 5G-related application services, and will also focus on the scene and physical display of typical 5G applications, while paying attention to the interactive experience of 5G and the immersive participation of visitors.

　　The information service section will show the application of new generation information technology and intelligent technology such as big data, artificial intelligence, industrial internet and intelligent robots in the field of urban environmental services.

　　The ultra-high-definition audio-visual service section will comprehensively display innovative technologies and products in all aspects of the industrial chain, such as video collection, production, transmission, presentation and application, covering all sub-categories of ultra-high-definition video and the whole upstream and downstream industrial chain of the industry. At the same time, it will also display the achievements of the ultra-high-definition video industry development pilot zone, 5G+8K innovation achievements, ultra-high-definition+application and other major industrial development achievements, and the only 5G+8K ultra-high-definition relay vehicle in the world will also be displayed on

　　The green technology service section of "Carbon Neutralization" will display mainstream cutting-edge technical services such as energy saving and carbon reduction, low-carbon technology, clean source application, energy storage technology, carbon capture and utilization (CCUS), carbon sink and ecological construction, and carbon market services to achieve the goal of "peak carbon dioxide emissions and Carbon Neutralization", and display high-level and high-standard green technologies through the mainstream formats of "peak carbon dioxide emissions and Carbon Neutralization" and forward-looking technical services to help "peak carbon dioxide emissions 2030"

　　Focus on frontier areas and highlight the level of internationalization

　　The special exhibition will focus on the frontier fields such as telecommunications, computers and information services, and focus on the new technologies, new products and new application scenarios of the industry, highlighting the highlights of internationalization, cutting-edge, interaction and transaction.

　　In order to improve the level of internationalization, 12 international enterprises and institutions, including Sony (China) Co., Ltd., Italian Robotics and Automation Association, institution of engineering and technology and ASEAN Intelligent Industry Federation, were invited to participate in the special exhibition. The major institutions and enterprises are aiming at the broad development prospects of telecommunications, computer and information services in China and the important opportunities for strengthening cooperation.

　　According to reports, the topic of telecommunications, computers and information services is planned to release seven achievements at this trade fair, including three achievements of clinching a deal. At present, the overall preparations for the exhibition are progressing smoothly, all the preparations have been made, and the enterprise exhibition is being carried out in an orderly manner. (Headquarters reporter Ji Lele Yu Jingjing)

　　Xinhua News Agency, Chengdu, March 20th Question: Have you found the answers to all the N kinds of legends about Sanxingdui?

　　Xinhua News Agency reporters Wang Peng, Shi Yuxi and Tong Fang.

　　With the announcement of new archaeological discoveries in Sanxingdui site, people’s eyes once again focus on this magical land.

　　Since the discovery of No.1 and No.2 "sacrificial pits" in Sanxingdui site in 1986, people have never stopped discussing it. A large number of shocking and mysterious cultural relics unearthed in the "sacrificial pit" have aroused a lot of speculation in the world.

　　Have you found the answers to those legends about Sanxingdui?

　　Legend 1: Is Sanxingdui an alien civilization?

　　Sanxingdui bronze vertical mask (Xinhua News Agency)

　　Huge ears, bulging eyes, and a big mouth wide to the ears … … Some people who eat melons believe that Sanxingdui is an alien civilization, and the grotesque bronze masks, bronze statues, bronze sacred trees and other cultural relics of Sanxingdui are alien works.

　　Experts are firmly opposed to this statement! The ancient Shu civilization, represented by Sanxingdui, is an important part of the pluralistic origin of Chinese civilization. Among the cultural relics unearthed in Sanxingdui, bronze statues, bronze rings, jade Zhang, jade cong, jade bi and jade ge are consistent with the Yellow River basin, which shows that Sanxingdui has the common attributes of Chinese culture. The familiar cultural relics with strange shapes and magnificent atmosphere, such as bronze standing man, bronze sacred tree and bronze vertical mask, not only show the brilliance of ancient Shu civilization, but also show the richness and diversity of Chinese culture.

　　In other words, Sanxingdui civilization is "made in China" and has nothing to do with aliens.

　　Legend 2: Sanxingdui people "moved" to Jinsha?

　　The gold mask unearthed from Jinsha site (left) and the newly discovered gold mask in Sanxingdui (imposition picture)

　　The newly discovered gold mask of Sanxingdui "made a stunning appearance", and the sharp-eyed netizens saw at a glance: this is the same as the gold mask of Jinsha! Not only the gold mask, but also the ornamentation, jade Zhang, jade chisel, ivory &hellip on the golden crown belt of Jinsha and the golden staff of Sanxingdui; … There are many cultural relics in the two sites. So can we think that people from Sanxingdui "moved" to Jinsha?

　　Experts believe that this high similarity between Jinsha site and Sanxingdui site proves that they belong to the same cultural system, and there must be some special connection between the two sites. Combined with the archaeological findings in recent years, we can think that Jinsha culture is the inheritance and development of Sanxingdui culture, and both of them have become an important part of the development of ancient Shu civilization.

　　Legend 3: Sanxingdui Archaeological Excavated "Angry Birds" with the same pig?

　　"Angry Birds" with the same pig (Xinhua News Agency)

　　Just last July, Sichuan Institute of Cultural Relics and Archaeology announced that an important site — — Joint site, unearthed a large number of cultural relics. Among them, a clay pottery pig is cute and cute, which is very similar to the villain green pig in Angry Birds. Netizens exclaimed: Is this the predecessor of Angry Birds?

　　In fact, experts believe that the joint site of this clay sculpture pottery pig unearthed should be an important settlement around the ruins of Sanxingdui ancient city. The joint site covers four cultural factors, namely, Guiyuan Bridge, Baodun Bridge, Sanxingdui Bridge and Twelve Bridges. It is the first time that a complete sequence of ancient Shu civilization has been found around Sanxingdui. Among them, the main cultural factors of Sanxingdui are the most abundant in the joint site, and a large number of cultural relics similar to Sanxingdui have been unearthed.

　　There are not only "villain green pigs", but also a large number of high-handled beans, hollowed-out beans (plates) and small flat-bottomed cans have been unearthed and restored at the joint site. It is worth mentioning that the pottery with the combination pattern of dragons and phoenixes carved on the yinxian line was unearthed in the late Shang Dynasty, and it is the earliest pottery with the pattern of "dragons and phoenixes are auspicious" found in China.

　　Legend 4: The "bronze giant" holds a "selfie stick" in his hand?

　　Sanxingdui "Bronze Man" (Xinhua News Agency)

　　Among the numerous bronze statues in Sanxingdui, the "bronze giant" is well known. Its overall image is solemn and solemn, and its hands are hollow. For a long time, people have been speculating whether he holds some kind of instrument in his hand. Even naughty netizens think that he is holding a "selfie stick" in his hand.

　　At present, there is no final conclusion on this issue in academic circles. Experts discussed that the "bronze standing man" may hold ivory, jade cong or scepter. The "Bronze Big Liren" wears a high crown, narrow sleeves and a half-arm-style three-layer dress, with complex and exquisite clothes, mainly dragon patterns, supplemented by bird patterns, insect patterns and eye patterns, and plaid stripes. It seems that his identity is an ancient Shu "high priest" with extraordinary skills.

　　There is no end to the exploration of Sanxingdui civilization.

　　Up to now, archaeologists have unearthed more than 500 important cultural relics in the six Sanxingdui cultural "sacrificial pits" newly discovered at Sanxingdui site.

　　I believe that in the future, through the detection and analysis of these cultural relics, more puzzles about Sanxingdui will be revealed. The true face of this ancient civilization, which has been buried deep underground for 3 thousand years, will become more and more clear.

　　We will wait and see … …

　　Throughout modern history, smallpox has held the top spot in killing human beings.

　　Smallpox is also the first infectious disease eliminated by human beings.

　　When future generations are exploring what killed smallpox, the trekking about how human beings overcome diseases step by step has merged into the long river of human medical history.

　　It is necessary for us to wade into this river at any time, go back to the way we came and find hope for the future.

　　The pockmarked emperor and the milkmaid

　　It is mentioned in Huangdi Neijing that "poison" should be used to treat diseases, and the so-called "fight poison with poison". Traditional Chinese medicine began to use this method to deal with smallpox, which existed during the Tang and Song Dynasties. Doctors take out the serous fluid from the abscess of smallpox patients and implant it into the body of healthy people for prevention and treatment, which is called human pox vaccination.

　　During the Wanli and Apocalypse years of Ming Dynasty, various books about human pox appeared. By the Qing dynasty, the method of preventing smallpox by human pox vaccination was widely promoted. Kangxi, the "pockmarked-faced emperor" who had suffered from smallpox, set up a pox clinic under the Tai Hospital and recruited famous doctors. Also in Beijing, a special "acne check chapter Beijing" is set up to take charge of the Eight Banners’ acne prevention. He specially sent people to welcome Ayla Zhang, a well-known folk vaccinia doctor, into the palace to vaccinate the royal family and banners.

　　Jared diamond, an evolutionary biologist and anthropologist, once revealed how the human body can defeat the virus: in the process of resisting a certain pathogen that infects the human body, the human body will gradually form specific antibodies, which makes it unlikely to be infected by the same pathogen again after recovery.

　　In the thousands of years of confrontation between human beings and smallpox, the latter has occupied an absolute advantage for a long time, and "pockmarked face" is so common that people without pockmarked face become special.

　　The 18th century was the age when smallpox ravaged Europe, and the British doctor edward Cenna (1749-1829) devoted himself to studying the solution. He noticed that almost all the female milkmaids had no "pockmarked faces". The beautiful milkmaid aroused Qinna’s curiosity, and he found one thing in common with them — — Cowpox of a milkmaid.

　　Vaccinia is a virus that can be co-infected by humans and animals, but it does no serious harm to cattle and people. There is a saying in the English countryside that "as long as you have suffered from vaccinia, you will not get smallpox".

　　Since 1788, Qinna began to carry out experiments on animals, using vaccinia of dairy women instead of smallpox patients to fight smallpox. For 8 years in a row, the experiment pointed to the same result, and vaccinia can effectively prevent smallpox.

　　On May 14th, 1796, Qinna conducted the first human experiment. He took the serous fluid Sarah Nelmes, a milkmaid, and inoculated it on the arm of phipps, an 8-year-old boy. Two months later, he inoculated phipps with real smallpox slurry. As a result, the boy was not infected with smallpox, and the previous vaccination seemed to have made him immune.

　　In the following two years, Qinna conducted the same human experiment many times, and the results were the same: all children who had had vaccinia were immune to smallpox virus. In 1798, Chennault announced that smallpox could be prevented by vaccination.

　　Vaccinium vaccination spread rapidly around the world. In 1977, Ethiopia recorded the last case of smallpox in human history. On October 26, 1979, WHO officially publicized that smallpox was eradicated all over the world.

　　This is the first time in human history to win the battle against infectious diseases.

　　Fatal bacteria and life-saving bacteria

　　Although the practical application of vaccinia technology is very successful, scientists are not satisfied. People need to explain theoretically why vaccinia can fight smallpox.

　　In the 1950s, chemist Louis Pasteur confirmed the relationship between diseases and germs, and found that specific microbial pathogens could cause specific diseases. Moreover, he found that the long-term growth toxicity of bacteria on artificial culture medium would be weakened, but the immunogenicity still existed.

　　According to this theory, in 1881, Pasteur artificially attenuated Bacillus anthracis with strong immunogenicity and inoculated it into sheep, which finally proved that sheep inoculated with Bacillus anthracis vaccine would not get the disease again.

　　Rabies virus can not be isolated and cultured like bacteria, but Pasteur confirmed that the pathogenic microorganism causing rabies exists in the spinal cord or brain tissue of sick animals. Therefore, he chose rabbit brain for subculture to obtain attenuated strains, and then successfully made live vaccines.

　　With the development of microbiology and immunology, vaccine is really defined as active immunity preparation for preventing infectious diseases, which is made of pathogenic microorganisms (such as bacteria, rickettsia, viruses, etc.) and their metabolites by artificial attenuation, inactivation or genetic engineering.

　　Based on this method, more vaccines can appear. Attenuated live vaccine made by heating inactivation of Vibrio cholerae; After 13 years and 213 generations of continuous culture on the culture medium, attenuated BCG was obtained.

　　With the development of the discipline, some traditional classical vaccine varieties have been further transformed into new vaccines, and some vaccines that cannot be developed with classical technology have found ways to solve the problem.

　　In 1972, recombinant genetic engineering contributed a lot of technical support and gave birth to recombinant gene vaccine. By using DNA recombinant biotechnology, natural or synthetic genetic material which can induce immune response in protein of pathogen shell can be directionally inserted into bacteria, yeast or mammalian cells, and the vaccine can be made after expression and purification. Nowadays, BCG, recombination vaccines, SARS vaccine, HIV vaccine and highly pathogenic avian influenza vaccine are being studied.

　　Conjugate vaccine appeared in 1980s. Scientists linked sugar molecules with protein (toxoid of Clostridium tetanus or diphtheria) by chemical methods, and developed a conjugate vaccine. Vaccines against pneumonia and meningitis are made in this way.

　　Looking at the present, the vaccine that has attracted much attention is none other than nucleic acid vaccine. Nucleic acid vaccine, also known as gene vaccine or DNA vaccine, transports DNA vaccine to human cells through some carrier (such as nanoparticles), which will guide the cells to produce immune active components, and then the cells will "spit out" these active components to stimulate the human body to obtain corresponding immunity, but it will not cause disease.

　　Nucleic acid vaccine can even transfect food cells, such as inserting hepatitis B virus nucleic acid vaccine into the genome of tomato cells, and inoculating the vaccine when eating tomatoes.

　　Scientific and technological progress brings infinite possibilities, and the new exploration of vaccination methods is also the tireless pursuit of scientists. In addition to traditional injection methods, oral administration, skin patch, nasal spray and improved fruit are all targets.

　　A never-ending struggle

　　With the development of immunology research, people have more and more expectations for vaccines, hoping that they will not only "prevent diseases". Researchers are already in action, trying to achieve the effect of treating diseases or preventing diseases from worsening by inducing specific immune responses. Such vaccine products are therapeutic vaccines.

　　There are many therapeutic vaccines that have been studied all over the world: tumor vaccines used for tumor treatment use tumor antigens for active immunization to stimulate the body’s active specific immune response to tumors to prevent the growth, spread and metastasis of tumors; Vaccines used for the treatment of cardiovascular diseases aim at intervening the immune process to prevent the occurrence and development of atherosclerosis (AS). A Swiss biotechnology company said that CYT006-AngQb, a vaccine used to treat hypertension, has a good clinical development prospect … …

　　On the other hand, when human beings are struggling to move forward, the "perpetrators" of infectious diseases are not willing to be silent. Since 1970s, more than 40 infectious diseases have been discovered in the world, such as HIV virus, avian influenza virus, SARS virus, mad cow disease prion, monkeypox virus, Lyme virus, Ebola virus, Legionella, Vibrio cholerae O139 and so on. People’s common influenza viruses are constantly innovating. For example, after the "Spanish flu" caused by H1N1 virus, the "Asian flu" and the "Hong Kong flu" were staged by H3N2 subtype virus. Or a lower-grade flu, it is staged almost every few years in Europe, America and Asia. There are also new viruses that have never met each other, eyeing and hiding in the dark.

　　"The only competitor competing with humans for the dominance of the earth is the virus." The words of lederberg, the winner of the Nobel Prize in Physiology or Medicine in 1958, sounded like an alarm bell. In the past two hundred years, the confrontation between human beings and germs was the fiercest. For the first time, we turned the tables, stood in a pre-emptive position, and seized the throat of the biggest killer of human beings. Compared with the end of the 19th century, the average life expectancy of human beings has been extended for several decades.

　　We have opened the "box" of vaccines. Overcoming the challenge of disease again and again makes us believe that disease creates problems and also provides understanding.

　　Huaxi Dushi Bao-cover journalist Li Yuanli

　　[References]

　　1. zhangfang, from human pox to cowpox [J], Science World, 06, 2018;

　　2. [America] jared diamond, Guns, Germs and Steel, Shanghai Translation Publishing House;

　　3. Huang Jiandong, the milestone of human conquest of smallpox — — Jenner’s Invention of Vaccinium Inoculation [J], Invention and Innovation, 2003, (9): 42-43;

　　4, Liu Xueli, China’s ancient immune thought and human pox vaccination [J], Medicine and Philosophy, 1993 (11);

　　5. Kou Yi, Brief Introduction of Three Vaccine Revolutions [J], Chinese Journal of Medical History;

　　6. Plotkin, Vaccine Science (5th Edition) (Fine), People’s Health Publishing House, 2011;

　　7. Xie Zhongping and Li Qihan, Fighting Infectious Diseases: Application and Development of Vaccines, 2007.